Hi Bob,
Here is a list of local tourism/travel and transport contacts that can help with hotel pick-up or sight-seeing in Panama City, whether collective or individual:
Road trips, tours (day tours, eco-tours, etc), ground transportation, airport pickups, etc:
• Panama Vacations, http://www.vacationtopanama.com
• Ancon Expeditions, http://www.anconexpeditions.com
• Roadrunner Panama, web: http://www.panamaroadrunner.com
• Inside Panama, email: transport@insidepma.com, tel: +507-6675-6601
• Panama Travel: http://www.panamatravelunlimited.com, info@panamatravelunlimited.com
• Sealandsky Journeys, email: ditase@yahoo.com, tel: +507-6630-0847
• Marco Colucci, tel: +507-6672-1201, email: macoluche@hotmail.com
There are more mentioned here along with user reviews:
http://www.tripadvisor.com/Attraction_Review-g294480-d2615043-Reviews-City_Sightseeing_Panama-Panama_City_Panama_Province.html
and
http://www.tripadvisor.com/Travel-g294480-c129835/Panama-City:Panama:Tour.Companies.html